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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPB41L5 All Species: 32.42
Human Site: S343 Identified Species: 54.87
UniProt: Q9HCM4 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCM4 NP_065960.2 733 81856 S343 S G F I R L G S R F R Y S G K
Chimpanzee Pan troglodytes XP_001157953 733 81845 S343 S G F I R L G S R F R Y S G K
Rhesus Macaque Macaca mulatta XP_001088764 726 81122 S333 R G P V Q K S S H R S G F I R
Dog Lupus familis XP_532028 914 101864 S425 S D F I R L G S R F R F S G R
Cat Felis silvestris
Mouse Mus musculus Q8BGS1 731 81617 S343 S G F I R L G S R F R Y S G K
Rat Rattus norvegicus Q5FVG2 731 81700 S343 S G F I R L G S R F R Y S G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509941 820 90648 P343 S Q A W G L R P A L P V V Q A
Chicken Gallus gallus XP_422083 502 57358 H117 I G P P Y C L H F R V K F Y S
Frog Xenopus laevis NP_001080234 498 57093 P113 K Q V K I G P P Y C L H L R V
Zebra Danio Brachydanio rerio O57457 619 70690 K234 P V G V V V Y K N K T Q V G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650291 972 105216 S358 Q N F F R M G S R F R Y S G R
Honey Bee Apis mellifera XP_623974 809 90976 S423 Q N F F R M G S R F R Y S G K
Nematode Worm Caenorhab. elegans P28191 1026 115075 S504 V R P V S S G S T P N G A S R
Sea Urchin Strong. purpuratus XP_788387 843 92835 S338 Q G F I R M G S R F R Y S G R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 95.2 39.8 N.A. 83.9 83.6 N.A. 56.5 56.6 54.4 28.5 N.A. 36.8 38.9 24.3 39.1
Protein Similarity: 100 99.3 96.3 52.1 N.A. 89.2 88.4 N.A. 65.1 62.2 60.9 44.7 N.A. 51.8 53.1 40.1 56.7
P-Site Identity: 100 100 13.3 80 N.A. 100 100 N.A. 13.3 6.6 0 13.3 N.A. 66.6 73.3 13.3 80
P-Site Similarity: 100 100 33.3 93.3 N.A. 100 100 N.A. 13.3 6.6 6.6 26.6 N.A. 80 80 33.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 8 0 0 0 8 0 8 % A
% Cys: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 58 15 0 0 0 0 8 58 0 8 15 0 0 % F
% Gly: 0 50 8 0 8 8 65 0 0 0 0 15 0 65 0 % G
% His: 0 0 0 0 0 0 0 8 8 0 0 8 0 0 0 % H
% Ile: 8 0 0 43 8 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 8 0 0 8 0 8 0 8 0 8 0 8 0 0 43 % K
% Leu: 0 0 0 0 0 43 8 0 0 8 8 0 8 0 0 % L
% Met: 0 0 0 0 0 22 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 15 0 0 0 0 0 0 8 0 8 0 0 0 0 % N
% Pro: 8 0 22 8 0 0 8 15 0 8 8 0 0 0 0 % P
% Gln: 22 15 0 0 8 0 0 0 0 0 0 8 0 8 0 % Q
% Arg: 8 8 0 0 58 0 8 0 58 15 58 0 0 8 36 % R
% Ser: 43 0 0 0 8 8 8 72 0 0 8 0 58 8 8 % S
% Thr: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % T
% Val: 8 8 8 22 8 8 0 0 0 0 8 8 15 0 8 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 8 0 8 0 0 50 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _